Purpose: This study was done to measure the degree of the hostility, perceived social support and health behavior compliance among patients with coronary artery disease and to identify the relationship among those variables. Methods: The participants were 145 hospitalized patients with coronary artery disease. Data were collected from December 15, 2007 to March 15, 2008 using a questionnaire and medical record. Results: Mean scores for hostility, perceived social support and health behavior compliance were 54.80, 53.03 and 59.38 respectively. Differences in the degree of hostility were significant for marital status and serum total cholesterol. There were significant differences in the degree of health behavior compliance according to body mass index, serum total cholesterol, smoking, drinking, exercise and regular diet. Health behavior compliance was correlated with hostility and perceived social support, and hostility was correlated with perceived social support. Conclusion: Intensive programs to enhance perceived social support but to reduce hostility are warranted to improve health behavior in patients with coronary artery disease.