Objectives: The purpose of this study is to be conducive to selecting effective educational method for AED(Automated External Defibrillator) education through comparing educational effects between VSI(Video Self-Instruction) and lecturer-centered learning on AED(Automated External Defibrillator) in undergraduates. Method: This study targeted totally 76 undergraduates (39 people for experimental group, 37 people for control group) at J university where is located in J province, from June 8, 2009 to June 12. The analytical method was performed by using SPSS WIN 12.0 Version program. Results: In difference before and after education of the skill performance accuracy in AED between groups, the experimental group(2.89) was higher compared to the control group(2.75). In difference before and after education of knowledge in AED between groups, the experimental group(2.03) was higher compared to the control group(1.82). In difference before and after education of attitude toward AED between groups, the control group(2.14) was higher compared to the experimental group(1.85). In difference before and after education of self-confidence in AED between groups, the experimental group(1.88) was higher compared to the control group(1.76).