Recently, a shipyard is making every effort to efficiently manage equipments of resources such as a gantry crane, transporter, and so on. So far block lifting scheduling of a gantry crane has been manually performed by a manager of the shipyard, and thus it took much time to get scheduling results and moreover the quality of them was not optimal. To improve this, a block lifting scheduling system of the gantry crane using optimization techniques was developed in this study. First, a block lifting scheduling problem was mathematically formulated as a multi-objective optimization problem, considering the minimization of travel distance at an idle state and wire replacement during block lifting. Then, to solve the problem, a meta-heuristic optimization algorithm based on the genetic algorithm was proposed. To evaluate the efficiency and applicability of the developed system, it was applied to an actual block lifting scheduling problem of the shipyard. The result shows that blocks can be efficiently lifted by the gantry crane using the developed system, compared to manual scheduling by a manager.