Purpose: The purpose of this study was to identify the predictors of clinical competence in new graduate nurses. Methods: The subjects of this study were 238 nurses at 13 general hospitals who have had less than 12 months of nursing experience. The data were collected by structured questionnaire from August 5 to August 31 of 2009 and analyzed by the SPSS Win 12.0 program. Results: The total mean score for clinical competence was $181.05{pm}15.17$, critical thinking disposition was $94.65{pm}8.12$, and practice environment was $41.00{pm}5.55$. There were significant differences of clinical competence according to the GPA (t=-3.58, p<.001), the number of beds in the hospital (t=-3.22, p=.001), instruction by preceptor (t=-2.32, p=.021), and previous experience of clinical practice in the hospital (t=-2.21, p=.028). Additionally, critical thinking disposition and practice environment were positively correlated to clinical competence (r=.50, p<.001; r=.20, p=.002). In multivariate approach, predictors included in this study explained 43% of variance in clinical competence. Significant predictors of clinical competence were critical thinking disposition ($eta=.50$, p<.001), practice environment ($eta=.14$, p=.012), and working duration ($eta=.13$, p=.018). Conclusions: Based on these findings, it is needed that providing supportive practice environment and developing curriculum for enhancing the critical thinking disposition to improve the clinical competence in new graduate nurses.