One of the most important objectives that apparel company will pursue in 21 century is to achieve the critical factors of the sustainability. The concept of sustainability is to meet the demands for the valuable life of contemporary generation and to satisfy the desires for preservation of the species and the productive life of future generation by protecting the earth environment from the waste and pollution and by developing and maintaining harmoniously main economical, social, environmental and cultural factors. The practice of sustainability was focused only on the environmental factors in past. Now, the effective and efficient practice of sustainability should be fulfilled and executed in social factors of the responsibility company has, in economical factors and in the cultural factors that is the critical in fashion industry. The purpose of the study is to develop the practical framework consisting of four sustainable factors which apparel brand should refer and apply to the practice of sustainability. By executing the practical factors of the frameworks, apparel company can take a lot of advantages. By practicing the environmental factors, company can get Eco-efficiency. Apparel company can take the social responsibility by performing social sustainable factors, can make economical quality growth by fulfilling economical sustainable factors, and can understand cultural diversity by executing cultural sustainable factors. As one of the most important preparation in 21 century industry, the apparel brand should have an interest in and require the practical management of sustainability, objective setting and practice of brand unit, reflection on the sustainability in brand planning.