Optimization of the turning process has been concentrated on the selection of the optimal cutting parameters, such as cutting speed, feed rate and depth of cut. However, optimization of the cutting parameters does not necessarily guarantee the maximum profit. For the maximization of the profit, parameters other than cutting parameters have to be taken care of. In this study, 8 price-related parameters were considered to maximize the profit of the product. Regression equations obtained from RSM technique to relate the cutting parameters and maximum cutting volume with a given insert were used. The experiments with four combinations of cutting inserts and material were executed to compare the results that made the profit and cutting volume maximized. The results showed that the cutting parameters for volume and profit maximization were totally different. Contrary to our intuition, global optimization was achieved when the number of inserts change was larger than those for volume maximization. It is attributed to the faster cutting velocity, which decreases processing time and increasing the number of tool used and the total tool changing time.