Novel Peracetylated N-Lactosyl-1,2,4-Thiadiazolidin-3-one Hydrochlorides: Synthesis and Antimicrobial Studies

Novel Peracetylated N-Lactosyl-1,2,4-Thiadiazolidin-3-one Hydrochlorides: Synthesis and Antimicrobial Studies
Novel Peracetylated N-Lactosyl-1,2,4-Thiadiazolidin-3-one Hydrochlorides: Synthesis and Antimicrobial Studies

ㆍ 저자명: Dandale. Anvita S.,Mangte. Dattatraya V.,Deshmukh. Shirish P.
ㆍ 간행물명: 대한화학회지
ㆍ 권/호정보: 2010년|54권 3호|pp.287-290 (4 pages)
ㆍ 발행정보: 대한화학회
ㆍ 파일정보: 정기간행물|ENG|
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ㆍ 주제분야: 기타

이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.

서지반출

영문초록

Peracetylated lactosyl carbamides와 N-phenyl-S-chloro isothiocarbamoyl chloride를 고리화 반응을 시켜서 peracetylated N-Lactosyl-1,2,4-thiadiazolidin-3-one hydrochlorides를 합성하였으며, 얻어진 화합물을 이용하여 bacteria S. aureus, E. coli, P. Vulgaris, P. Aeruginosa and fungi A. Niger, Penicillium 항균 활성을 연구하였다.

기타언어초록

In the present work we described oxidative cyclisation of peracetylated lactosyl carbamides with N-phenyl-S-chloro isothiocarbamoyl chloride and structural elucidation of novel peracetylated N-Lactosyl-1,2,4-Thiadiazolidin-3-one hydrochlorides. Antimicrobial activities of the title compounds were determined against bacteria S. aureus, E. coli, P. Vulgaris, P. Aeruginosa and fungi A. Niger, Penicillium.

키워드

고리화 합성 항균활성 Peracetylated lactosyl carbamides Isothiocarbamoyl chloride Cyclisation Peracetylated lactosyl thiadiazolidin-3-one Synthesis Antimicrobial activity

다운URL