Severe energy constraints and the low power consumption require the significance of the energy efficient error control mechanisms in wireless sensor network (WSN). In this paper, an automatic repeat request (ARQ) methodology for the analysis of error control schemes in WSN is presented such that the effects of packet length, the modulation scheme and the interference effect of the wireless channel are investigated. Moreover, an analyis of ARQ error control is provided by considering two major architectures for wireless sensor network, i.e., Mica2 and MicaZ sensor nodes. And the throughput performance of WSN with asynchronous FSK signal and DSSS-OQPSK signal with selective repeat ARQ scheme are analyzed in multiple interference environment, and the probability of receiving a correct bit and packet from target node to sink node is evaluated as a function of the channel parameter, the number of wireless sensor node, and the spreading factor.