The effects of the tentering-extension rates and repeated washing on the mechanical properties and hand values of cotton/ spandex twill were examined. A 3% spandex containing cotton twill was treated by tenter extension at different rates of 0%, 5%, 10% and 15%. The processed fabric with a 0% extension rate was also dyed using a reactive dye. The KES-FB system was utilized to measure the mechanical properties of the twill, and the basic and total hand values were determined using a KN-201-MDY and KN-301-WINTER, respectively. The fabrics treated with greater tentering extension and dried in a clothes tumble dryer showed lower bending and shear properties, and became softer and smoother. The greatest change in the mechanical properties and hand values occurred after the first wash, but the differences in the washed and unwashed state decreased with increasing number of wash cycles. These results show that cotton/spandex twill should be extended 5% during tentering to yield less deterioration of the T.H.V., and be dried in a clothes tumble dryer to maintain a soft and smooth hand without affecting the shrinkage and elasticity.