기관회원 [로그인]
소속기관에서 받은 아이디, 비밀번호를 입력해 주세요.
개인회원 [로그인]

비회원 구매시 입력하신 핸드폰번호를 입력해 주세요.
본인 인증 후 구매내역을 확인하실 수 있습니다.

회원가입
서지반출
Combining Fructooligosaccharide and Dried Plum Has the Greatest Effect on Restoring Bone Mineral Density Among Select Functional Foods and Bioactive Compounds
[STEP1]서지반출 형식 선택
파일형식
@
서지도구
SNS
기타
[STEP2]서지반출 정보 선택
  • 제목
  • URL
돌아가기
확인
취소
  • Combining Fructooligosaccharide and Dried Plum Has the Greatest Effect on Restoring Bone Mineral Density Among Select Functional Foods and Bioactive Compounds
  • Combining Fructooligosaccharide and Dried Plum Has the Greatest Effect on Restoring Bone Mineral Density Among Select Functional Foods and Bioactive Compounds
저자명
Arjmandi. Bahram H.,Johnson. Catherine D.,Campbell. Sara C.,Hooshmand. Shirin,Chai. Sheau C.,Akhter. Mohammed P.
간행물명
Journal of medicinal food
권/호정보
2010년|13권 2호|pp.312-319 (8 pages)
발행정보
한국식품영양과학회
파일정보
정기간행물|ENG|
PDF텍스트
주제분야
기타
이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

Functional foods and=or their bioactive compounds playing a role in improving skeletal health have received considerable attention. The objective of the present study was to determine the extent to which certain functional foods as (1) whole, e.g., dried plum (DP), figs, dates, raisin, and blueberry, (2) fractionated, e.g., DP puree, DP juice, and DP pulp/skin, or (3) isolated, e.g., DP polyphenols, fructooligosaccharides (FOS), and ${eta}$-hydroxy-${eta}$-methylbutyrate, forms reverse bone loss in an ovariectomized (Ovx) rat model of osteoporosis. Additionally, some of these components were tested in reversal of bone loss in combination. For this purpose, 180 3-month-old female Sprague-Dawley rats were divided into 15 groups (n=12) and either Ovx (14 groups) or sham-operated (Sham, one group). Rats were maintained on a semipurified standard diet for 45 days after surgery to establish bone loss. Thereafter, rats were placed on one of the following dietary treatments for 60 days: caseinbased diet (Sham and Ovx). The remaining 13 Ovx groups were placed on various treatment diets. Results showed that diets supplemented with 5% FOS+7.5% DP was most effective in reversing both right femur and fourth lumbar bone mineral density and fourth lumbar calcium loss while significantly decreasing trabecular separation. There were no significant effects of treatment on serum or urine measures of bone turnover. Although other treatments were good at altering some bone parameters, none had the success in altering several bone health indicators as the diets supplemented with 5% FOS+7.5% DP. The findings of this study suggest the combination of 5% FOS+7.5% DP is capable of reversing Ovx-induced bone loss.