Exhausting fossil fuel and increasing concern of air pollution have brought on the change of the focus of developing new vehicles from performance to fuel economy and emission. The gasoline engines adopting the naturally aspirated way use the throttle-body for engine load control. Therefore, its pumping loss increases more than that of the diesel engine, and also mostly operating in a partial load condition has bad influence on fuel economy and emission. In these days, the continuous variable valve timing system and variable induction system are adopted in order to improve fuel consumption and emission. In this study, we optimize the runner length and operate region of variable induction system to simulataneously improve the performance, fuel economy, and emission of gasoline engine with employing GT-Power as a CAE tool for engine analysis and PIAnO as PIDO tool for process integration and design optimization.