In sensor signal conditioning and processing, offset and drift characteristics of an operational amplifier are an important factor when the amplifier is used for a precise sensor signal amplifier. In order to use it in high accuracy, an expensive trimming or a complex compensation circuit is required. This paper presents the improved sensor signal conditioning and processing device for ubiquitous sensor network(USN) application or general purpose by developing a hardware of the circuit for reducing the offset voltage and drift characteristics, and a software for its control and sensor signal processing. We realize better offset voltage and drift characteristics of the signal conditioning circuit using low cost operational amplifiers. The experimental results show that this technique is effective in improving the performance of the sensor signal processing device.