Site characterization on geological and geotechnical conditions was performed for evaluating the earthquake ground motions associated with seismic site effects at a small urbanized area, Hongseong, where structural damages were recorded by an earthquake of magnitude 5.0 on October 7, 1978. In the field, various geotechnical site investigations composed of borehole drillings and seismic tests for obtaining shear wave velocity profile were carried out at 16 sites. Based on the geotechnical data from site investigation and additional collection in and near Hongseong, an expert system on geotechnical information was implemented with the spatial framework of GIS. For practical application of the GIS-based geotechnical information system to assess the earthquake motions in a small urban area, spatial seismic zoning maps on geotechnical parameters, such as the bedrock depth and the site period ($T_G$), were created over the entire administrative district of Hongseong town, and the spatial distributions of seismic vulnerability potentials were intuitively examined. Spatial zonation was also performed to determine site coefficients for seismic design by adopting a site classification system based on $T_G$. A case study of seismic zonation in the Hongseong area verified that the GIS-based site investigation was very useful for regional prediction of earthquake ground motions in a small urbanized inland area.