Three-dimensional structural analysis system for nuclear containment building is presented in this paper. This system includes high-performance plate/shell elements as finite element library. It also adopts numerical modeling technique for unbonded tendon as well as bonded tendon in prestressed concrete structures. This system is constructed by connecting several in-house program to a commercial program DIANA, and then is capable of performing nonlinear analysis for ultimate pressure capacity of nuclear containment building. Finally, three-dimensional structural analysis of CANDU-type containment building is carried out in order to test the reliability of this system. These numerical results are compared with reference values, which obtained from axisymmetric structural analysis.