Purpose: The purpose of this study was to explore the relationships between Yangsaeng and quality of life (WHOQOL-BREF) of Korean adults and older people practicing Dan Jeon Breathing. Methods: The participants were 133 adults and elderly people practicing Dan Jeon Breathing. Data were collected by self-reported questionnaires, which were constructed to include Yangsaeng and quality of life (WHOQOL-BREF). Frequency, percentage, mean standard deviation, t-test, ANOVA, Scheffe test, Pearson correlation coefficient, and Cronbach ${alpha}$ value were used with the SPSS 14.0 win program to analyze the data using for finding. Results: Significant differences in Yangsaeng were evident on the basis of age, gender, duration of DJB, regular practice of DJB, and other exercises. There were significant differences in quality of life in terms of existence of spouse and duration of DJB. Also, all subcategories in Yangsaeng were positively related to all domain of quality of life. Conclusion: The results indicate that the quality of life of adult and elderly Koreans who practice DJB is more closely associated with Yangsaeng. Therefore, Dan Jeon Breathing can be utilized as a nursing intervention for Yangsaeng and quality of life of Koreans.