The purpose of this study was to identify the effect of the craniocervical posture on swallowing and hyoid bone movement with sitting posture in wheelchair, and to provide basic data for developing a treatment program for dysphagia. A total of sixty healthy adults without a history of dysphagia who were guardians or care assistants of inpatients at Hospital K underwent video fluoroscopy performed by physiatrists from April to July 2009. The results of the fluoroscopy were analyzed based on the measurement of hyoid bone movements. The hyoid bone movement(horizontal, vertical, and diagonal) was significantly high in the neutral craniocervical, chin-tuck, and sixty degrees extension postures, in descending order(p<.05). It was found that the neutral craniocervical posture is the most effective posture for hyoid bone movement with sitting posture in wheelchair.