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태음조위탕(太陰調胃湯)과 태음조위배마황탕(太陰調胃培麻黃湯)이 비만 흰쥐에 미치는 영향
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  • 태음조위탕(太陰調胃湯)과 태음조위배마황탕(太陰調胃培麻黃湯)이 비만 흰쥐에 미치는 영향
저자명
양동혁,김재현,정종길,정현우,최찬헌,Yang. Dong-Hyuk,Kim. Chae-Hyun,Jung. Jong-Gil,Jung. Hyun-Woo,Choi. Chan-Hun
간행물명
大韓本草學會誌
권/호정보
2010년|25권 3호|pp.103-109 (7 pages)
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Objective : The aim of this study is to investigate the effects of Taeyeumjoweetang (TJT) and Taeyeumjoweebaemahwangtang (TJBM) medication on body weight change and serum total cholesterol, HDL cholesterol, LDL cholesterol, triglyceride, free fatty acid, total lipid, phospholipid level, and CBC of obese rats. Methods : Obese rats induced by high-fat fed are medicated for 7 weeks. 32 rats are divided into four groups depending on the medication; normal group (general-fat fed and no-medication), control group (high-fat fed and no medication), TJT group (high-fat fed and TJT medication) and TJBM group (high-fat fed and TJBM medication). After 7 weeks, obesity related index and CBC are analysed. Results : There is a significant statistical difference between control group and TJBM group for the body weight change, the total cholesterol, HDL cholesterol, and triglyceride level: total cholesterol values of control and TJBM are $59.25{pm}9.56 mg/d{ell}$ and $39.13{pm}9.08 mg/d{ell}$, respectively; HDL cholesterol values of control and TJBM are $22.0{pm}1.69 mg/d{ell}$ and $13.75{pm}2.19 mg/d{ell}$, respectively; triglyceride values of control and TJBM are $12.75{pm}3.37 mg/d{ell}$ and TJBM : $8.13{pm}1.64 mg/d{ell}$, respectively. There is a significant statistical difference between control group, TJT, and TJBM group for free fatty acid and phospholipid level: free fatty acid values of control, TJT, and TJBM are $936.25{pm}89.59 {mu}m/{ell}$, $738.75{pm}109.47{mu}m/{ell}$, and $720{pm}150.71{mu}m/{ell}$, respectively; phospholipid values of Control, TJT, and TJBM are $87.13{pm}11.86mg/d{ell}$, $70.5{pm}12.22 mg/d{ell}$, and $60.5{pm}11.1 mg/d{ell}$, respectively. Conclusion : These results suggest that medication of TJT and TJBM is effective for the treatment of obesity. Especially, TJBM is more effective than TJT.