Purpose: The aim of this study was to examine the characteristics of hypertension-related nursing intervention programs and their effects on systolic and diastolic blood pressure. Methods: Fifteen studies were selected from four databases (Korean studies, Riss4U, RICHIS, and JKAN) published as of 2009. They were analyzed by meta-analysis method. The selected studies contained a control group with pre-test and post-test design, measured blood pressure as a dependent variable, and used a reported statistical value for blood pressure to measure the size of effects. Results: The hypertension-related nursing intervention programs were relatively effective in lowering both systolic and diastolic blood pressure, although they were more efficient to decrease diastolic pressure. Among the hypertension-related intervention programs, complementary and alternative therapies were more effective in lowering blood pressure compared to lifestyle change intervention. Conclusions: To acquire substantial data of intervention effects, and complementary and alternative therapy, subjects in pre-hypertensive stage, and elderly people, better industrial and scholastic research methods need to be developed for future research. Further studies are needed to establish complementary and alternative therapies. Studies with different group of participants and studies using effective research design are in need as well.