In this study, we intended to design the optimal Fermi filter to apply the k-space date that is knee image of the rheumatoid arthritis patient acquired from the MRI (magnetic resonance imaging) instrument. After deciding the suitable coefficient for the Fermi filter, the results were compared with modified Fermi filter and inverse Chebyshev filter, Chebyshev filter, Elliptic filter and Butterworth filter. Firstly, in comparison to the results, the radiologist confirmed that modified Fermi filter was best decision for boundary of the rheumatoid arthritis images. The number of the black voxels of the histogram showed the quantity of the results. At the proposed filter images, numbers of the blacks voxels were statistically decreased. That meant voxels only appeared the black color were changed to others voxels color. Because the number of the total voxels was fixed, the area appeared block color could be effected to the other areas. If the modified Fermi filter were used for rheumatoid arthritis patient, the result will be better than other filters.