The use of the friction coefficient is known to provide good discrimination ability in the classification of human constitutions, which are used in alternative medicine. In this study, a system that uses a multi-axis load cell and a hemi-circular probe is designed. The equipment consists of a sensor (load cell type, manufactured by the authors), an x-axis linear-bush guide motorized mobile stage that supports the hand being analyzed, and a signal conditioner. Using the proposed system, the friction coefficients from different constitutions were compared, and the relative repeatability error for the friction coefficient measurement was determined to be less than 2 %. The direction along the ring finger line was determined to be the optimum measurement region for a constitutional diagnosis between Tae-eumin and Soyangin types using the proposed system. There were some differences in the friction coefficient between the two constitutions, as reported in ancient literature. The proposed system is applicable to a quantitative constitutional diagnosis between Tae-eumin and Soyangin types within an acceptable level of uncertainty.