Recently, earthquake proof technology has been widely applied to both new and existing structures and bridges. The analysis of bridge systems equipped with structural control devices, which possess large degrees of freedom and nonlinear characteristics, is a result in time-consuming task. Therefore, a piecewise exact solution is proposed in this study to simplify the seismic mitigation analysis process for bridge systems equipped with sliding-type isolators. In this study, the simplified system having two degrees of freedom, to reasonably represent the large number of degrees of freedom of a bridge, and is modeled to obtain a piecewise exact solution for system responses during earthquakes. Simultaneously, we used the nonlinear finite element computer program to analyze the bridge responses and verify the accuracy of the proposed piecewise exact solution for bridge systems equipped with sliding-type isolators. The conclusions derived by comparing the results obtained from the piecewise exact solution and nonlinear finite element analysis reveal that the proposed solution not only simplifies the calculation process but also provides highly accurate seismic responses of isolated bridges under earthquakes.