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Indirect Determination of Cetirizine Hydrochloride by ICP-AES
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취소
  • Indirect Determination of Cetirizine Hydrochloride by ICP-AES
  • Indirect Determination of Cetirizine Hydrochloride by ICP-AES
저자명
Wang. Li-Sheng,Wei. Xiao-Ling,Gong. Qi,Jiang. Zhi-Liang,Li. Dong-Mei,Liang. Qing
간행물명
Bulletin of the Korean Chemical Society
권/호정보
2011년|32권 2호|pp.595-598 (4 pages)
발행정보
대한화학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Cetirizine hydrochloride reacted with $BiI_4^-$ in an acidic aqueous solution to form precipitate. After centrifugation, the atomic emission intensity of $Bi^{3+}$ contained in the supernatant solution was measured at the characteristic wavelength of 206.170 nm. The difference between the spectral signal intensity of the blank solution and that of the supernatant, ${Delta}I$, was linearly related to the concentration of cetirizine hydrochloride. As a result, a new inductively coupled plasmaatomic emission spectrometric (ICP-AES) method was developed for the analysis of cetirizine hydrochloride. The linear range was from 27.7 to 184.8 $mg{cdot}L^{-1}$, with a correlation coefficient (r) of 0.9961 and a detection limit of 9.6 $mg{cdot}L^{-1}$. This method is simple and accurate, Without using toxic organic solvents, and is feasible for the quality control of cetirizine hydrochloride tablets and capsules.