Gyeongnam province is well known for its high concentration on machinery manufacturing industry. However, this province is losing competitive advantage due to the lack of IT S/W industry. In this paper, we propose a way for adoption of u-Manufacturing technology to promote IT S/W industry in Gyeongnam. At first, we identified the needs of manufacturing companies and the capabilities of the IT S/W companies with survey. Based on the survey analysis, then we set up the u-Manufacturing concept and proposed Manufacturing IT middleware to support it. Finally, we proposed a strategy to promote smoothly the adoption of u-Manufacturing technology in this area.