Objectives : The purpose of this study was to investigate the effect of treatment with Sacro-Occipital Technique block on musculoskeletal pain caused by traffic accident by analysis of the Visual Analogue Scale(VAS), Neck Disability Index(NDI), Pain Disability Index(PDI), Oswestry Low back Pain Disability Index(ODI) and Short Form - McGill Pain Qusetionnaire (SF-MPQ). Methods : This study carried out on 18 patients who have received hospital treatment in Daejeon Univ. Dun-San Oriental Hospital. Control group got acupunture-therapy, herbal medication, physical therapy and Experimental group got all the therapies and treatment with Sacro-Occipital Technique block. We measured VAS, NDI, PDI, ODI and SF-MPQ on 1st day and 7 days later. Results : After being treated by our methods, Both group were improved in VAS, NDI, PDI, ODI, and SF-MPQ. Especially, Experimental group was significantly meaningful improved in VAS, PDI, and ODI. Control group was significantly meaningful improved in VAS and SF-MPQ. But, differences between control and experimental group were nonsignificant. Conclusions : The results suggest that treatment with Sacro-Occipital Technique block is not significantly meaningful but gives a positive impact on musculoskeletal pain caused by traffic accident. But further long term study in a large scale is needed.