Hybrid acceleration-impedance sensor nodes on Imote2-platform are designed for damage monitoring in steel girder connections. Thus, the feasibility of the sensor nodes is examined about its performance for vibration-based global monitoring and impedance-based local monitoring in the structural systems. To achieve the objective, the following approaches are implemented. First, a damage monitoring scheme is described in parallel with global vibration-based methods and local impedance-based methods. Second, multi-scale sensor nodes that enable combined acceleration-impedance monitoring are described on the design of hardware components and embedded software to operate. Third, the performances of the multi-scale sensor nodes are experimentally evaluated from damage monitoring in a lab-scaled steel girder with bolted connection joints.