Infra-Red Dark Clouds (IRDCs) seen silhouette against the bright Galactic background in mid-IR are a class of interstellar clouds that are dense and cold with very high column densities. While IRDCs are believed to be the precursors to massive stars and star clusters, individual IRDCs show diverse star forming activities within them. We report a remarkable example of such cloud, the IRDC at ${Gamma}53.2^{circ}$, and star formation activity in this cloud. The IRDC was previously identified in part as three separate, arcmin-size clouds in the catalogue of MSX IRDC candidates, but we found that the IRDC is associated with a long, filamentary CO cloud at 2 kpc from the Galactic Ring Survey data of $^{13}CO$ J = 1-0 emission, and that its total extent reaches ~ 30pc. The Spitzer MIPSGAL 24mm data show a number of reddened mid-IR sources distributed along the IRDC which are probably young stellar objects (YSOs), and the UWISH2 $H_2$ data (2.122mm) reveal ubiquitous out flows around them. These observations indicate that the IRDC is a site of active star formation with YSOs in various evolutionary stages. In order to investigate the nature of mid-IR sources, we have performed photometry of MIPSGAL data, and we present a catalogue of YSOs combining other available point source catalogues from optical to IR. We discuss the evolutionary stages and characteristics of YSOs from their IR colors and spectral energy distributions.