Currently, melamine is being used variously in our lives such as resins, flame retardants, adhesive, laminate etc. And understandably sewer of stream of wastewater containing Melamine has also increased. GHS (Globally Harmonized System of Classification and Labelling of Chemicals) of EU safety guidelines says that it can cause cancer. Still, study on toxicity of Melamine is going on. In this research, melamine contamination level of the Han River and River Basin was analyzed by HPLC/UV. And the experiments of GAC adsorption were conducted and the model was studied. We collected the 3 same samples at the suburbs of Paldang Dam located in the relative upstream in Han River and Ttukseom amusement park, the downstream region and collected samples equally at the Hongreung stream, Wangsuk stream, Cheonggye stream among streams flowing into Han River and then measured Melamine concentration after purification. As a result, melamine was not detected at the suburbs of Paldang Dam and it was detected at Ttukseom amusement park, the downstream of it, in the concentration of $0.312{mu}g/L$. The Wangsuk stream with $0.578{mu}g/L$ highest Cheonggye stream and Hongreung stream was detected with each $0.197{mu}g/L$ and $0.325{mu}g/L$. Although the concentration was low in general, melamine detection could be checked at most point. In 1970, the world capacity of Melamine was estimated at 200,000 ton, with current production estimated to be 1,400,000 ton. Melamine of Han River and rivers flowing into Han River is present at low concentration but pollution will increase in the future due to increase of use. Depending on the size of activated carbon in the experiment were slightly different. But the breakthrough model is almost identical.