Red wine has become very popular, in part for its professed health benefits. Anthocyanin pigments, which are the main components of the pigments in red wine, are changed in the molecular structures and the color with the solution having different alkalinity and metals. The color changes of a red wine soiled cloth after washing in various pHs and water hardness solutions were studied. Distilled and tap water, which have lower water hardness, showed the highest $L^*$ value and lowest $a^*$ and $b^*$ values at pH 9. The detergent with added oxygen bleach was more effective in removing red wine soil, even though its pH was 10.8. The effect of the red wine removal with the solution where bleach was added separately was much lower than with the solution of the detergent containing bleach. Water hardness greatly affected the color of the cloth, soiled with red wine after washing. That is, the color was the faintest when the cloth was washed with the bleach-added detergent solution having 0 ppm of water hardness. An effective and economical method or equipment for removing metals in a washing solution for a washing machine should be developed to enhance the stain and soil removal.