Entropy used for measuring the richness in details of the image and absolute mean brightness error(AMBE) providing a change in the image global appearance are two quantitative measures generally used for measuring quality of images. In this paper, we propose an entropy and AMBE-based thresholding method to binalize a given image. The effectiveness of the proposed method is demonstrated by thresholding experiments on nine test images and comparison with other conventional thresholding methods, that is, Otsu method and entropy-based method.