The purpose of this study is to assess vulnerability of vehicle bomb attack of high rise buildings in Korea. For this objective, 4 layers of defense and 17 architectural design elements were deduced on the basis of domestic and foreign anti-terrorism guidelines. Weights of 4 layers and 17 elements were developed through the AHP survey of anti-terrorism specialists. The potential vulnerability of bomb attack of 10 high rise offices in Seoul were assessed based on the model. The result indicates that there were no significant difference of overall vulnerability among all buildings and the vulnerability level was found to be medium. Among 4 layers of defense, the vulnerability of 2nd layer was the highest and the vulnerability of 3rd layer showed more variation among the buildings assessed. In conclusion, several cost-effective architectural design options to mitigate potential vehicle bomb attack were suggested.