Objectives : This study aimed to design manual of guideline book for combined medicaion of the oriental and the western drugs in the disease of the aged. Method : First, we collected informations about guideline book for drug medication, and we investigated wishes of professors who are working for an oriental medicine at universities. Result & Conclusion : 1. The greater part of professors recognized necessity of guideline book for combined medicaion of the oriental and the western drugs. 2. The basic stages of framing guideline book for combined medicaion of the oriental and the western drugs are as follows. The first step is planning of framing guideline book for combined medicaion of the oriental and the western drugs. The second step is organization of framing group and advisory committee for guideline book. The next steps are searching the core of items and making a searching all the literature and estimating the literature. And then, we should complete basic contents of guideline book in a row, and those must be examined thoroughly by external experts. Finally we can make public the guideline book for combined medicaion of the oriental and the western drugs. If there are reform contents in the guideline book, we can amend contents and make public the revision guideline book again. 3. We need guideline information center for combined medicaion of the oriental and the western drugs in the disease of the aged for framing, wide-spread and development of guideline book. 4. We think that the guideline information center should be composed of a steering committee, a committee of controlling informations and advisory committee for guideline book.