Tilt-rotor aircraft can be used in various fields because they have the capabilities of the vertical take-off and landing and the high-speed cruise flight. In the present study, the flow analysis of a tilt-rotor aircraft is conducted at various tilt angles. The lift and drag forces of the tilt-rotor aircraft are obtained and the wakes by the rotor-blade are visualized. The result shows that the rotor-blade affects the lift force in a hovering mode and the main wing has an influence on the lift force in a cruise mode. Additional thrust is required at the tilt angle of around 40 degree due to the least lift force. The drag force is dependent on the rotor-blade at overall tilt angles. The minus drag force appears between the tilt angles of 90 degree and 55 degree. Also, the drag force is dramatically increased at the other tilt angles. The wake by rotor-blade affects the flow around the fuselage of the tilt-rotor aircraft at the tilt angles of 75 degree and 60 degree.