The purpose of this study was to identify the correlations between disease related factors and disturbance of daily living in patients with fibromyalgia. A descriptive survey study design was used. Data were collected from 45 out patients diagnosed of fibromyalgia according to the conditions by American College of Rheumatology in I-city. The mean score of tender points were 15.00, fatigue was 8.67, quality of sleep was 12.94 and depression was 23.70. They have struggled with fibromyalgia for 6 years on an average. Among patients, 42.2% had to discontinue their job/learning due to their disease, and experienced a disturbance of daily living for 41.79 days during last 3 months. There were significant positive correlations between disturbance of daily living and tender points, depression, between fatigue and depression, quality of sleep, between quality of sleep and depression. As a result, fibromyalgia patients suffered from various disease related factors and disturbance of daily living. Therefore, it can be suggested that the consideration of these related factors is important to develope intervention program for the better qualified life of the patients.