Groundwater monitoring data from the National Groundwater Monitoring Stations, a total of 320 stations, were analyzed to identify the response of water level and quality to the Odaesan earthquake (M4.9) occurred in January 2007. Among the total of eight stations responded to the earthquake, five wells showed water-level decline, and in three wells, water level rose. In terms of recovery, water levels in four stations had recovered to the original level in five days, but not in the rest four wells. The magnitude of water-level change shows weak relations to the distance between the earthquake epicenter and the groundwater monitoring station. However, the relations to the transmissivities of monitored aquifer in the station with the groundwater change were not significant. To implement the earthquake monitoring system through the groundwater monitoring network, we still need to accumulate the long-term monitoring data and geostatistically analyze those with hydrogeological and tectonic factors.