On Android environment, program development is conducted with JAVA SDK. However, using JAVA, it is operated over virtual machine which shows lower performance in terms of speed than traditional C language programming. The method writes program in C language, which conducts operation efficiently. In the paper, we implement multiplication using NDK and SDK to analyze the public key cryptography over Android environment. In case of SDK, we used BigInteger package and in case of NDK, we used Comb method. Moreover, execution time of arithmetic, branch and call operations over Android environment is compared to understand performance enhancement using NDK package.