In this paper, an efficient scheme for correcting rotated objects in medical images using the Mojette transform is presented. The Mojette transform is a kind of discrete Radon transform, where the transform domain is represented by a set of projections. The Mojette transform currently studied in the image compression area is modified for detecting the rotation angle of objects in medical images. First, in order to find accurate rotation angle, the projection value in the Mojette transform is determined by using pixels on the projection line and in addition the linear interpolation of pixels adjacent to the line. Second, at each projection angle, only one projection is implemented for reducing the amount of the calculation in the process of the Mojette transform. Finally, the projection in the Mojette transform is carried out at the predetermined ROI(Region Of Interest) at which the objects are not cropped or added by rotating the image. The simulation results show that the proposed method has good performance for correcting the rotation angle in medical images.