While the extruded cement panel has many advantages compared to drywall, it has limited applicability in buildings due to its low fire resistance. However, an extruded panel in which the fire resistance has been dramatically enhanced through the addition of a-hemihydrate gypsum is expected to become widely applied as a partition wall or interior material for buildings. To ensure its applicability, certain safety requirements for use, such as the leaning load by residents, the impact by indoor articles, and the fire, need to be taken into consideration. The purpose of this study is to review the impact load resistance, horizontal load resistance, and fire resistance as required safety properties for the partition wall and interior materials of the extruded panel that includes a-hemihydrate gypsum. The results of this study show that the impact load resistance of the extruded panel that includes a-hemihydrate gypsum achieves SD grade for industrial buildings, and the horizontal impact load resistance achieves HD grade for public buildings. In addition, it provides fire-resistance for approximately 7 minutes longer than the existing extruded cement panel. Based on this result, it is confirmed the extruded panel incorporating a-hemihydrate gypsum has adequate safety properties for use as partition wall or interior material.