This paper reports the irradiation effect on the deformation behavior and tensile fracture properties of A533B RPV steel. An inverse identification technique using iterative finite element (FE) simulation was used to determine those properties from tensile data for the A533B RPV steel irradiated at 65 to $100^{circ}C$ and deformed at room temperature. FE simulation revealed that the plastic instability at yield followed by softening for higher doses was related to the occurrence of localized necking immediately after yielding. The strain-hardening rate in the equivalent true stress-true strain relationship was still positive during the necking deformation. The tensile fracture stress was less dependent on the irradiation dose, whereas the tensile fracture strain and fracture energy decreased with increasing dose level up to 0.1 dpa and then became saturated. However, the tensile fracture strain and fracture energy still remained high after high-dose irradiation, which is associated with a large amount of ductility during the necking deformation for irradiated A533B RPV steel.