A 160 MW drum-type boiler-turbine system is developed in the present research through a multi-multivariable dynamic matrix control (DMC) scheme and a multi-multivariable model approach. A novel intelligence-based decision mechanism (IBDM) is realized to support both model approach and control scheme. In such case, the responsibility of the proposed IBDM is to identify the best multivariable model of the system and the corresponding multivariable DMC scheme to cope with the system at each instant of time in an appropriate manner.