In the present work, numerical analyses of air flow in HVAC duct have been carried out for enhancement of cooling/heating performance. For the analyses, three-dimensional Reynolds-averaged Navier-Stokes equations have been solved with the shear stress transport turbulence model. The numerical results were validated in comparison with the experimental data. Based on the numerical results, the HVAC duct was designed to reduce the pressure loss. The modified duct geometry shows largely reduced pressure drop in comparison with the reference geometry. And, through modified duct shape, the performance of air conditioning has been enhanced.