The object of this study was to find out the effect of various reinforcing materials including Quarts Splint$^{TM}$ Mesh on the transverse strength of the denture resin. QC-20 and Lucitone199$^{(R)}$ were used as the denture resin, and polyethylene fiber Ribbond$^{(R)}$, light curing quarts fiber Quarts Splint$^{TM}$ Mesh, metal mesh were used as the reinforcing materials. Ten specimens were fabricated for each group and the size of specimens was $2.0{ imes}10.0{ imes}65.0mm$. To compare the effect of resin thickness, additional specimens of $2.5{ imes}10.0{ imes}65.0mm$, $3.0{ imes}10.0{ imes}65.0mm$ were fabricated. In the control group, the transverse strength of Lucitone199$^{(R)}$ was significantly higher than that of QC-20(p<0.05). Among the specimens of 2.0 mm thickness fabricated with $Lucitone199^{(R)}$ and QC-20, they showed high transverse strength in the order of metal mesh, Quarts Splint$^{TM}$ Mesh, Ribbond$^{(R)}$, and control group. In the specimens of 2.0 mm, 2.5 mm thickness, the transverse strength of Quarts Splint$^{TM}$ Mesh were significantly higher than that of QC-20(p<0.05). But in the specimens of 3.0 mm thickness, there was no significant difference.