This study proposes an active control method to suppress beam-rotating machinery system vibrations. The present control method is a combination of the fuzzy input estimation method (FIEM) and linear quadratic Gaussian problem (LQG) algorithms. The FIEM can estimate the unknown input and optimal states by measuring the dynamic displacement, the optimal estimated states into the feedback control; thereby obtaining the optimal control force for a random linear system. Active vibration control of a beam-rotating machinery system is performed to verify the feasibility and effectiveness of the proposed algorithm. The simulation results demonstrate that the proposed method can suppress vibrations in a beam-machine system more efficiently than the conventional LQG method.