Infrared dark clouds(IRDCs) are believed to be the progenitors of massive stars and clusters. We obtained 350 and 850 ${mu}m$ continuum maps of the IRDC G049.40-00.01 using SHARC-II on CSO. Twenty-one dense clumps were identified within G049.40-00.01 based on the 350 ${mu}m$ continuum map with an angular resolution of about 9.6". We present submillimeter continuum maps and report physical properties of the clumps. The masses of clumps are from 50 to 600 solar mass. About 70% of the clumps are associated with bright 24 ${mu}m$ emission sources indicating protostars. The most massive two clumps show enhanced, extended 4.5 ${mu}m$ emission representing on-going star forming activity. The size-mass distribution of the clumps suggests that many of them are forming high-mass stars. G049.40-00.01 contains numerous objects in various evolutionary stages of star formation, from pre-stellar clumps to H II regions.