The purpose of this paper is to analyze the structural relationship of the impact on the business performance when it pursues resource based production strategies, nurtures core competency, develops core product lines and innovate its business models as part of a strategy of value innovation and to validate how the nurturing core competency can have an impact on the execution of the value innovation strategies. This paper confirms that there is a structural relationship, which is logically and conceptually valid, among the core competence, value innovation strategies and business performance of manufacturing companies. In order to maximize the business performance which is the eventual objective of a company, it must strategically nurture its core competence, which will be a main driver of the future competitiveness and diversify its management based on the value innovation strategies.