This paper presents a two-dimensional (2D)-based approach to the problem of output feedback repetitive control for uncertain discrete-time systems. It is shown first how the proposed repetitive control scheme can be equivalently formulated in the form of a distinct class of 2D system. Then sufficient conditions for the existence of output feedback control law are derived in terms of linear matrix inequality (LMI), and the control law matrices are characterized by the feasible solutions to this LMI. Moreover, an optimization problem is introduced to efficiently solve the optimal output feedback control law by minimizing the upper bound of a given cost function. Compared with the commonly used 1D-based method, the proposed approach increases the degree of freedom of controller design by not only including in the scheme an output feedback gain but also a feed forward one which can be simultaneously solved using the 2D-based procedures presented in the paper. Finally, a numerical example is provided to demonstrate the effectiveness of the proposed method.