This study was to investigate the origin of meridian through the relationship between Five Su Points and arteriovenous anastomosis. We searched traditional studies about origin of merdian and papers on relationship origin of merdian and blood vessels. As bibliographic search results, we got the conclusion that it is funtion of arteriovenous anastomosis and its anatomical position. Next we compared relationship between it and merdian. We found that Jeong-Acupuncture Points of Five-Su Points and Geun-Acupuncture Points of merdian have close relate to anatomical position(similarities). When we compared relationship between arteriovenous anastomosis and hypertension, we found that Biao Acupuncture Points and Geun Acupuncture Points of merdian have close relate to regulation of blood pressure and blood circulation. According to this results, Five Su Points and arteriovenous anastomosis have close relationship in anatomical position and regulatory function of blood pressure.