This paper studies the application of a fuzzy-ARTMAP (FAM) neural network to multi-user detector (MUD) for direct sequence (DS)-code division multiple access (CDMA) system. This method shows new solution for solving the problems, such as complexity and long training, which is found when implementing the previously developed neural-basis MUDs. The proposed FAM based MUD is fast and easy to train and includes capabilities not found in other neural network approaches; a small number of parameters, no requirements for the choice of initial weights, automatic increase of hidden units, no risk of getting trapped in local minima, and the capabilities of adding new data without retraining previously trained data. In simulation studies, binary signals were generated at random in a linear channel with Gaussian noise. The performance of FAM based MUD is compared with other neural net based MUDs in terms of the bit error rate.