Supramolecular ordering via self-assembly of amide dendrons was investigated in different solvents. The selection of the solvents strongly affected the supramolecular ordering of third generation dendrons depending on the solubility strength while only a minimal effect was seen with the first and second generation dendrons. The number of amide branches and alkyl tails which are responsible for the hydrogen bond and steric hindrance determined the solvent effect. Relatively low numbers of branches in the first and second generation dendrons compared with the third generation resulted in the minimal solvent effect. Solutions of low solubility favoring collapsed and extended conformation of third generation dendrons induced lamellar superstructure, while solutions of high solubility favoring expanded globular conformation formed columnar superstructures. The results were discussed based on the Kamlet-Taft parameters of the solvents.