1. Objective : It is well-known that even if some people are born with same constitution, their symptoms can be different according to Exterior and Interior diagnosis. This study aimed to suggest different clinical symptoms according to Exterior and Interior group in individual Sasang constitution. 2. Methods : We collected 706 physiological and pathological data of subjects from August 2009 to July 2011 using case report form of Questionnaire. The Sasang constitutional diagnosis and Exterior and Interior diagnosis were conducted by Sasang constitutional experts. All data were analyzed with Chi-square test and significant p value was 0.05. 3. Results : There are different symptoms between Exterior and Interior group in Taeeumin as followed, the frequence of famine and burp, the part of sweat, brown or not in color of stool, painful or not in evacuating, the frequence of loose feces, the frequence of abdominal inflating, the costive feeling frequence after evacuating, foam in urine or not, urination times, amount of Coldness and Hotness in belly, the frequence of turning fale in face. Soeumin as followed, digestion well or not, amount of sweat in exercise, the brown or not in color of stool, the frequence of turning fale in face, athe frequence of clearness in urine and feeling hot. Soyangin as followed, amount of appetite, amount of sweat in hot weather, sweat in neck or not, the red color in urine or not, Coldness and Hotness in foot or not, amount of drinking. 3. Conclusions : We may suggest that physiological and pathological symptoms are different between exterior and interior group in individual Sasang constitution respectively.