In this paper, we suggested the method of signal integrity for noises and distortion signal generated between high speed information transmission modules by external effects. Suggested method for signal integrity of impedance matching to remove transmission line distortion, We divided the impedance matching between the transmitter and the receiver module with the single line and differential line methods after confirmed the improvement of signal distortions through ADS simulation. the experimental results indicated that it is possible to keep signal integrity without signal distortions by matching the optimal termination impedance which are considering the signal delay of transmission line for using the high-performance modules.